Data mining the SNP information for hub genes identified for mouse in the current (SLC2A4, TNFRSF1B, TRFR2, and UCHL1) and our previous study (HPXN, NID2 and FLT1) was retrieved from National Centre for Biotechnology Information (NCBI) database dbSNP (http://www.ncbi.nlm.nih.gov/projects/SNP). Three different programs (PROVEAN, SIFT and POLYPHEN-2) were used to predict the damaged or deleterious coding nsSNPs.